We will show a result for the query Carazolol (3-letter PDB code:CAU). Carazolol is the partial inverse agonist for beta-2 adrenergic receptor. Following similar compounds to the query are shown after 1-2 minututes. Among these compounds, a user can choose compounds for further analysis for their interacting proteins, by clicking the radio buttons. The value "Tanimoto" shows the ratio of matched atoms, which ranges from 0 to 1. In this case, compounds with Tanimoto > 0.7 were checked.Finaly、the button is clicked.
Then, the list of proteins binding to one of the six chosen compounds is shown. As we expected, the beta-1 and beta-2 adrenergic receptors were included in the list. Surprisingly, similar compounds to the carazolol can bind two enzymes, exoglucanse 1 (SNP, XX6, XX7) and lactotransferrin (RNP). From this result, we can hypothesize that the carazolol may bind to exoglucanase 1 and lactotransferrin.
If one of the 3D icons is clicked, following 3D models are shown.