ID   NS8_WCPV                Reviewed;         121 AA.
AC   P0DTC8;
DT   22-APR-2020, integrated into UniProtKB/Swiss-Prot.
DT   22-APR-2020, sequence version 1.
DT   22-APR-2020, entry version 1.
DE   RecName: Full=Non-structural protein 8;
DE            Short=ns8;
DE   Flags: Precursor;
OS   Wuhan seafood market pneumonia virus.
OC   Viruses; Riboviria; Nidovirales; Cornidovirineae; Coronaviridae;
OC   Orthocoronavirinae; Betacoronavirus; unclassified Betacoronavirus.
OX   NCBI_TaxID=2697049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Wu F., Zhao S., Yu B., Chen Y.-M., Wang W., Hu Y., Song Z.-G., Tao Z.-W.,
RA   Tian J.-H., Pei Y.-Y., Yuan M.L., Zhang Y.-L., Dai F.-H., Liu Y.,
RA   Wang Q.-M., Zheng J.-J., Xu L., Holmes E.C., Zhang Y.-Z.;
RT   "A novel coronavirus associated with a respiratory disease in Wuhan of
RT   Hubei province, China.";
RL   Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in host-virus interaction. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Simnilar to some Bat coronavirus ns8 genes, but is
CC       entirely different from SARS ns8a or Ns8b. {ECO:0000305}.
CC   -!- MISCELLANEOUS: nCoV is the prototype of the virus isolated during the
CC       severe coronavirus outbreak in originated in Wuhan in 2020.
CC       {ECO:0000305}.
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DR   EMBL; MN908947; QHD43422.1; -; Genomic_RNA.
DR   InterPro; IPR022722; Corona_NS8.
DR   Pfam; PF12093; Corona_NS8; 1.
PE   3: Inferred from homology;
KW   Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..121
FT                   /note="Non-structural protein 8"
FT                   /id="PRO_0000449655"
SQ   SEQUENCE   121 AA;  13831 MW;  912AD9E147A64907 CRC64;
     MKFLVFLGII TTVAAFHQEC SLQSCTQHQP YVVDDPCPIH FYSKWYIRVG ARKSAPLIEL
     CVDEAGSKSP IQYIDIGNYT VSCLPFTINC QEPKLGSLVV RCSFYEDFLE YHDVRVVLDF
     I
//